Drug discovery: a research sector stricken in France that can sometimes pay off

The emerging academic drug-discovery sector.

Can Agents Be Better-Off with Pay Caps?

Imposing caps on managers’ pay has been a popular way to discipline managers of companies or banks that got into trouble during the recent financial crisis. Using a small extension of the standard principal-agent model, we argue that pay caps may serve the opposite purpose because the agent can be better off with a pay cap. Specifically, we show that, given a fixed effort level to be implemente...

Teamwork on the line can pay off down the line

Purpose – Employees’ work in innovation processes generates ideas, but more often it serves to create conditions so that new products or services can be effectively produced or delivered. Self-organizational activities involve proactively handling new possibilities, unexpected situations, problems or tasks. The aim of this paper is to provide support for a previously proposed model of the deter...

Can Monkeys Make Investments Based on Maximized Pay-off?

Animals can maximize benefits but it is not known if they adjust their investment according to expected pay-offs. We investigated whether monkeys can use different investment strategies in an exchange task. We tested eight capuchin monkeys (Cebus apella) and thirteen macaques (Macaca fascicularis, Macaca tonkeana) in an experiment where they could adapt their investment to the food amounts prop...

Drug Discovery Research for Hydrocephalus

In 2013, clinical and basic science research has rolled the dice further to extend our understanding to hydrocephalus. A group of research team at Boston Children’s Hospital and Harvard Medical School, led by neurosurgeon, Joseph Madsen, has published the laboratory investigation results on vascular endothelial growth factor, VEGF, and showed its potential effect on the development of experimen...